Microfluidic chip held between fingersGrid of stained tissue microarray samplesTwelve's AirPlant One carbon transformation plant at dusk

Founders are unlocking the power of science with technology and expanding the frontier of what’s possible.

Breakout Ventures has spent more than a decade investing at this edge.

Frontier Focus Advantage

Breakout has been an incredible thought partner, helping me think through everything from big strategic decisions around our business model and financing to the details of how we tell our story. They understand the complexity of building a science-driven company and know how to help founders navigate it.

Ron Alfa, MD, PhD

Noetik

Rigorous Partnership

Breakout has been the kind of investor you genuinely want in your corner. They believed in us early, took the time to understand what we’re building, and have been thoughtful and engaged partners ever since. They know when to lean in, where they can make a difference, and how to support us through the moments that matter most.

Ivana Muncie-Vasic, PhD

Vitra Labs

Catalytic Network

A lot of investors will tell you they have the right network. With Breakout, I've seen it in action. Breakout knew the corporates, the strategic partners, and the next-stage investors we needed before we ever asked. That's made a real difference in how we scale the company.

Harshal Chokhawala, PhD

ZymoChem

Scientific innovation changes what’s possible.

Scaling innovation into breakout companies changes our future.

Meet the companies delivering on the promise of science.

Leveraging advanced machine learning to discover and develop cancer therapies

Noetik trains self-supervised foundation models on one of the largest multimodal human tumor datasets in existence to predict clinical outcomes and simulate therapeutic effects before drugs ever reach the clinic.

Whether you've launched your company or are doing the heavy lifting to get to the starting line, let’s talk.

Let's Talk